Christopher P Evans Selected Research

2- (dibenzo(b,d)furan- 2- yl)- 7- phenyl- 1- (3- (piperidin- 1- yl)propyl)- 1H- imidazo(4,5- g)quinoxalin- 6(5H)- one

1/2013

CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitors.

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Christopher P Evans Research Topics

Disease

109	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 03/2004
72	Neoplasms (Cancer) 01/2022 - 10/2002
17	Neoplasm Metastasis (Metastasis) 12/2020 - 03/2004
10	Renal Cell Carcinoma (Grawitz Tumor) 10/2019 - 05/2006
9	Urinary Bladder Neoplasms (Bladder Cancer) 10/2016 - 10/2002
6	Carcinoma (Carcinomatosis) 01/2019 - 10/2002
4	Kidney Neoplasms (Kidney Cancer) 05/2011 - 10/2005
3	Carcinogenesis 01/2018 - 12/2007
3	Thrombosis (Thrombus) 01/2018 - 02/2015
3	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 03/2007 - 09/2002
2	Cardiovascular Diseases (Cardiovascular Disease) 10/2021 - 03/2020
2	Melanoma (Melanoma, Malignant) 12/2020 - 12/2019
2	Non-Muscle Invasive Bladder Neoplasms 01/2018 - 10/2007
2	Disease Progression 01/2018 - 04/2009
2	Fatigue 01/2017 - 07/2014
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2017 - 10/2002
2	Hypertension (High Blood Pressure) 07/2014 - 04/2008
2	Urologic Neoplasms (Urological Cancer) 05/2011 - 02/2009
2	Transitional Cell Carcinoma 02/2010 - 05/2003
2	Testicular Neoplasms (Testicular Cancer) 01/2004 - 02/2003
2	Lower Urinary Tract Symptoms 08/2003 - 09/2002
1	Genetic Risk Score 01/2022
1	Leukemia 10/2020

Drug/Important Bio-Agent (IBA)

38	Androgen Receptors (Androgen Receptor)IBA 01/2021 - 03/2004
37	AndrogensIBA 11/2021 - 03/2004
26	enzalutamideIBA 01/2021 - 08/2013
12	Hormones (Hormone)IBA 01/2022 - 01/2005
12	abirateroneIBA 01/2022 - 03/2015
9	Docetaxel (Taxotere)FDA Link 01/2022 - 09/2013
8	Prostate-Specific Antigen (Semenogelase)IBA 01/2022 - 06/2004
8	Androgen Antagonists (Antiandrogens)IBA 01/2020 - 03/2009
6	Pharmaceutical PreparationsIBA 01/2018 - 03/2010
6	Interleukin-6 (Interleukin 6)IBA 09/2015 - 03/2009
6	saracatinibIBA 06/2010 - 04/2008
5	cabazitaxel FDA Link 10/2021 - 06/2017
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 06/2013
5	MicroRNAs (MicroRNA)IBA 07/2014 - 12/2007
5	src-Family KinasesIBA 06/2012 - 04/2008
4	AntigensIBA 01/2022 - 03/2009
4	LigandsIBA 01/2022 - 08/2013
4	Gonadotropin-Releasing Hormone (GnRH)FDA Link 10/2021 - 11/2011
4	Niclosamide FDA Link 01/2021 - 06/2014
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 02/2009
4	apalutamideIBA 01/2021 - 03/2015
4	Small Interfering RNA (siRNA)IBA 11/2020 - 04/2008
3	acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamide FDA Link 10/2021 - 10/2019
3	Leuprolide (Lupron)FDA LinkGeneric 10/2021 - 10/2019
3	taxaneIBA 10/2021 - 10/2018
3	Phosphotransferases (Kinase)IBA 12/2019 - 02/2007
3	Testosterone (Sustanon)FDA Link 10/2019 - 08/2009
3	bicalutamide (Casodex)FDA LinkGeneric 01/2017 - 03/2009
3	Biological ProductsIBA 03/2015 - 02/2007
3	Tyrosine Kinase InhibitorsIBA 01/2010 - 03/2004
3	NeuropeptidesIBA 03/2009 - 01/2009
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 07/2019
2	olaparibIBA 01/2022 - 07/2019
2	DNA (Deoxyribonucleic Acid)IBA 11/2021 - 01/2020
2	darolutamideIBA 01/2021 - 01/2020
2	Taxoids (Taxanes)IBA 01/2020 - 10/2018
2	RNA (Ribonucleic Acid)IBA 01/2020 - 01/2020
2	UbiquitinIBA 10/2019 - 11/2018
2	SteroidsIBA 10/2019 - 04/2015
2	Proteasome Endopeptidase Complex (Proteasome)IBA 10/2019 - 11/2018
2	Indomethacin (Indometacin)FDA LinkGeneric 01/2017 - 04/2015
2	TOR Serine-Threonine KinasesIBA 01/2016 - 05/2012
2	Chloroquine (Aralen)FDA LinkGeneric 09/2014 - 01/2010
2	Dasatinib (BMS 354825)FDA Link 12/2013 - 02/2007
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2013 - 06/2012
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2013 - 03/2004
2	sanguinarineIBA 01/2012 - 03/2010
2	SurvivinIBA 01/2012 - 03/2010
2	AlkaloidsIBA 01/2012 - 03/2010
2	andrographolideIBA 02/2011 - 08/2010
2	Tyrosine (L-Tyrosine)FDA Link 01/2010 - 02/2007
1	COVID-19 VaccinesIBA 01/2022
1	Phenobarbital (Luminal)FDA Link 11/2021
1	Prednisone (Sone)FDA LinkGeneric 01/2021
1	aminophenylacetylleucine (APAL)IBA 01/2021
1	EpitopesIBA 12/2020
1	AutoantibodiesIBA 12/2020
1	Steryl-Sulfatase (Steroid Sulfatase)IBA 11/2020
1	omega-Chloroacetophenone (Mace)IBA 03/2020

Therapy/Procedure

64	Castration 11/2021 - 02/2007
58	Therapeutics 01/2022 - 09/2002
11	Drug Therapy (Chemotherapy) 10/2021 - 05/2007
9	Radiotherapy 01/2022 - 05/2007
9	Nephrectomy 10/2019 - 04/2008
8	Prostatectomy (Retropubic Prostatectomy) 01/2021 - 12/2007
7	Lymph Node Excision (Lymph Node Dissection) 01/2021 - 02/2003
7	Thrombectomy 10/2019 - 09/2014
5	Cystectomy 10/2016 - 09/2004
2	Precision Medicine 01/2022 - 02/2009
2	Aftercare (After-Treatment) 11/2021 - 02/2010
2	Immunotherapy 12/2020 - 05/2007
2	Salvage Therapy 11/2020 - 08/2008
2	Length of Stay 01/2018 - 08/2015
2	Neoadjuvant Therapy 10/2016 - 09/2004
2	Brachytherapy 05/2012 - 06/2007
2	Palliative Care (Palliative Therapy) 04/2011 - 10/2005
2	Adjuvant Chemotherapy 09/2009 - 10/2007